|Normal Open Sutures in Infant Skull (Pink)|
|Copyright © Nucleus Medical Media, Inc.|
- Parents with the disorder
- Parents who do not have the disorder, but who carry the gene that causes the disorder.
- Fathers at an older age at the time of conception
- Flattened top and back of head
- Flattened forehead and temples
- Mid-face that is small and located further back in the face than normal
- Beaked-like nose
- Compression of nasal passages, often causing reduced airflow through the nose
- Large, protruding lower jaw
- Misalignment of teeth
- High-arched, narrow palate, or cleft palate
- Problems with development of inner ear and hearing loss
- Meniere’s disease (dizziness, vertigo, or ringing in the ears)
- Problems with the eyes including vision problems, crossed eyes or involuntary eye movement
- Curvature of the spine
- Acanthosis nigricans (small, dark, velvety patches of skin)
- Hydrocephalus—build up of fluid in the skull
- Craniectomy—removal and replacement of portions of the skull. Done as early as possible after birth to prevent damage to the brain. It will also help to maintain a skull shape that is as normal as possible.
- Surgery to treat protrusion of one or both eyeballs—adjustments are made to the bones surrounding the eye sockets.
- Surgery to treat protruding lower jaw—to normalize the appearance of the jaw.
- Surgery to repair a cleft palate.
Eye and Ear Treatment
Cleft Palate Foundation http://www.cleftline.org/
National Institute of Health Office of Rare Diseases http://rarediseases.info.nih.gov/
The Centre for Craniofacial Care and Research at SickKids http://www.sickkids.ca/craniofacial/
Abnormal timing in the prenatal ossification of vertebral column and hand in Crouzon syndrome. Am J Med Genet . 2000 Feb 28.
Craniosynostosis. EBSCO DynaMed website. Available at: https://dynamed.ebscohost.com/about/about-us . Updated November 28, 2011. Accessed December 27, 2012.
Dalben Gda S, Costa B, Gomide MR. Oral health status of children with syndromic craniosynostosis. Oral Health Prev Dent . 2006;4(3):173-9.
Perlyn CA, Morriss-Kay G, Darvann T, Tenenbaum M, Ornitz DM. A model for the pharmacological treatment of crouzon syndrome. Neurosurgery . 2006 Jul;59(1):210-5.
Crouzon Syndrome. NIH Office of Rare Disease website. Available at: http://rarediseases.info.nih.gov/GARD/QnASelected.aspx?diseaseID=6206 . Accessed December 27, 2012.
- Reviewer: Michael Woods, MD
- Review Date: 11/2012 -
- Update Date: 11/26/2012 -