Acute Cerebellar Ataxia
Acute Cerebellar Ataxia
(Cerebellitis)
Definition
| Cerebellum (Darker Pink Section) |
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Causes
-
Viral infections, including:
- Chickenpox
- Coxsackie disease
- Epstein-Barr virus
- Mycoplasma pneumonia
- HIV infection
- Lyme disease
- Exposure to certain toxins, such as lead , mercury , thallium, alcohol , and organophosphates found in insecticides
- Cerebellar hemorrhage, abscess, blood clot, or obstruction of an artery
- Paraneoplastic syndromes—occurs when the immune system attacks the cerebellum
- Stroke
- Malformation of the cerebellum
- Multiple sclerosis
- Migraine or vertigo
- Genetic or metabolic disorders
- Autoimmune diseases, such as anticardiolipin antibody syndrome
- Brain tumor
- Alcoholism
- Seizures
Risk Factors
- Age, especially children three years of age or younger
- Viral infections
- Recent vaccination
- Exposure to certain insecticides, drugs, or toxins
Symptoms
- Uncoordinated movements of the limbs or trunk
- Clumsiness with daily activities
- Difficulty walking
- Speech disturbances with slurred speech and changes in tone, pitch, and volume
- Visual complaints
- Abnormal eye movements
-
Accompanying symptoms may include:
- Headache
- Nausea and vomiting
- Dizziness
- Changes in mental state, such as personality or behavioral changes
- Chaotic eye movements
- Clumsy speech pattern
Diagnosis
-
You may need to have your bodily fluids and tissues tested. This can be done with:
- Lumbar puncture
- Blood tests
- Urine analysis
- You may need to have pictures taken of your bodily structures. This can be done with:
- You may need to have your nerve and muscle activity tested. This can be done with:
Treatment
- Corticosteroids
- IV immune globulin
- Plasma exchange therapy
- Clonazepam
- Amantadine
- Gabapentin
- Buspirone
Prevention
RESOURCES
National Ataxia Foundation http://www.ataxia.org
National Institutes of Neurological Disorders and Stroke http://www.ninds.nih.gov
CANADIAN RESOURCES
Canadian Institutes of Health Research http://www.cihr-irsc.gc.ca
Health Canada http://www.hc-sc.gc.ca
References
Berman P. Ataxia in children. International Pediatrics . 1999:14:44-47.
Bradley WG, Daroff RB. Neurology in Clinical Practice . Philadelphia, PA: Butterworth Heinemann Publishing; 2004.
Cerebellar ataxia. BBC News website. Available at: http://news.bbc.co.uk/1/hi/health/medical%5Fnotes/4055425.stm . Accessed February 22, 2013.
Cerebellar ataxia. EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed . Updated November 13, 2012. Accessed February 22, 2013.
Cerebellar ataxia. Patient UK website. Available at: http://www.patient.co.uk/showdoc/40001724/ . Accessed February 22, 2013.
Encephalopathy. National Institute of Neurological Disorders and Stroke website. Available at: http://www.ninds.nih.gov/disorders/encephalopathy/encephalopathy.htm . Updated November 9, 2010. Accessed February 22, 2013.
Frequently asked questions. University of Chicago Ataxia Center website. Available at: http://ataxia.uchicago.edu/FAQ.aspx . Accessed February 22, 2013.
Ishikawa N, Kobayashi M. Recurrent acute cerebellar ataxia associated with anti-cardiolipin antibodies. Brain Dev . 2009; Aug 22.
Mehta SH, Morgan JC, Sethi KD. Paraneoplastic movement disorders. Curr Neurol Neurosci Rep . 2009;9(4):285-91.
Ropper AH, Brown RH. Adams and Victor's Principles of Neurology . 8th ed. New York, NY: McGraw-Hill Medical Publishing Division; 2005: chap 33.
Stumpf DA. Acute ataxia. Pediatr Rev . 1987;8;303-306