Further studies are needed to identify alcohol's role in exacerbation or severity of illness
THURSDAY, Aug. 29 (HealthDay News) -- Alcohol consumption seems to be associated with increased endometriosis risk, according to a meta-analysis published in the August issue of the American Journal of Obstetrics & Gynecology.
Fabio Parazzini, M.D., from the University of Milan, and colleagues conducted a literature review to identify all full-length, case-control and cohort studies published as original articles in English up to May 2012.
The researchers found that, based on 15 included studies, for any alcohol intake versus no alcohol intake, the summary estimate was 1.24. The relative risk estimates were 1.14 (95 percent confidence interval [CI], 0.86 to 1.52), 1.23 (95 percent CI, 1.08 to 1.40), and 1.19 (95 percent CI, 0.99 to 1.43) for infrequent, moderate/regular, and heavy alcohol intake, respectively, versus no alcohol intake. For current and former drinkers (reported in three studies), the relative risk estimates were 1.42 (95 percent CI, 1.14 to 1.76) and 1.09 (95 percent CI, 0.83 to 1.43), respectively.
"The present meta-analysis provides evidence for an association between alcohol consumption and endometriosis risk," the authors write. "Further studies are needed to clarify whether alcohol consumption may exacerbate an existing disease or could be related to the severity of the disease."
Abstract (http://www.ajog.org/article/S0002-9378(13)00528-0/abstract )Full Text (subscription or payment may be required) (http://www.ajog.org/article/S0002-9378(13)00528-0/fulltext )